Flucloxacillin IV 2g 6 hourly (4 hourly if endocarditis suspected)

If true beta-lactam allergy or MRSA suspected then:

Vancomycin IV (dosing info here)

Course duration: 14 days IV or as advised by infection specialist.

All patients require echo and investigation for possible underlying source.

Replace intravascular device, if source of infection.

Discuss management (including duration of therapy) with microbiology / infectious diseases unit.

Repeat blood cultures after 48-96 hours of effective therapy.

To aid appropriate management complete SAB sticker.